Platelet Rich Fibrin (PRF)

Tear trough, wound healing, scar revision and hair restoration

Plasma rich fibrin (PRF) is a biological material derived from a patient's own blood and is used in various medical and aesthetic procedures. It is a second-generation platelet concentrate that contains a high concentration of platelets, growth factors, cytokines, and other bioactive molecules.

The process of obtaining PRF involves a simple blood draw from the patient. The blood is then centrifuged to separate the different components. Unlike platelet-rich plasma (PRP), which typically requires the addition of anticoagulants, PRF is obtained without any additives. In aesthetics is user facial rejuvenation such as tear trough, wound healing, scar revision and hair restoration.

  • For hair restoration it is recommended 3-4 treatment sessions, separated by 30-60 days then 1-2 treatments per year for maintenance.
  • Procedure takes 30-45 minutes. For tear trough rejuvenation at least 3 treatments 4-6 weeks apart with individualized yearly maintenance.
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How is PRF prepared?

During an outpatient procedure, a small amount of blood is drawn from the patient via an IV and placed in a centrifuge machine. The machine spins the blood to separate the PRF from the red blood cells.

What are some common side effects?

PRF injections can cause redness, swelling, or bruising at the treatment site, but these side effects usually go away within a few days. Other side effects may include pain that worsens before it improves, numbness, heaviness, or a pins and needles feeling.

How long do results lasts?

A typical treatment takes about 30-45 minutes. During the procedure, you may feel a slight pinch, but the procedure is generally well-tolerated.

When will I see results and how long do they last?

Initial results from PRF injections usually appear after 4–8 weeks, and results can continue to improve for 3–6 months. As you are regenerating collagen, lasting results will depend on the care and maintenance of your skin. The collagen that you build from this treatment is what you will keep for a lifetime.

What areas can be treated with PRF?

PRF is safe and can be placed around the eyes, cheeks and mid face, loose skin on the face and neck, back of hands and décolletage.

What are the benefits of PRF?

  • Tissue regeneration and rejuvenation
  • Neo – Collagenesis
  • Neo – Vascularization
  • Extracellular Matrix formation
  • Non allergenic since it is a ‘body own’ physiological product vs. animal derived or human donor products
  • Biological Glue: for tissue adhesion especially in skin flaps, bone grafts and trauma

What are the contraindications to PRF?

You should not have a PRF injection if you have the following:

  • Cancer or metastatic disease
  • An active infection
  • A low platelet count
  • Pregnant/Breastfeeding.
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